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Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India

Saxena, Richa ; Saleheen, Danish ; Been, Latonya F. ; Garavito, Martha L. ; Braun, Timothy ; Bjonnes, Andrew ; Young, Robin ; Ho, Weang Kee ; Rasheed, Asif ; Frossard, Philippe ; Sim, Xueling ; Hassanali, Neelam ; Radha, Venkatesan ; Chidambaram, Manickam ; Liju, Samuel ; Rees, Simon D. ; Ng, Daniel Peng-Keat ; Wong, Tien-Yin ; Yamauchi, Toshimasa ; Hara, Kazuo ; Tanaka, Yasushi ; Hirose, Hiroshi ; Mccarthy, Mark I. ; Morris, Andrew P. ; Basit, Abdul ; Barnett, Anthony H. ; Katulanda, Prasad ; Matthews, David ; Mohan, Viswanathan ; Wander, Gurpreet S. ; Singh, Jai Rup ; Mehra, Narinder K. ; Ralhan, Sarju ; Kamboh, M. Ilyas ; Mulvihill, John J. ; Maegawa, Hiroshi ; Tobe, Kazuyuki ; Maeda, Shiro ; Cho, Yoon S. ; Tai, E. Shyong ; Kelly, M. Ann ; Chambers, John C. ; Kooner, Jaspal S. ; Kadowaki, Takashi ; Deloukas, Panos ; Rader, Daniel J. ; Danesh, John ; Sanghera, Dharambir K.

Saxena, R., D. Saleheen, L. F. Been, M. L. Garavito, T. Braun, A. Bjonnes, R. Young, et al. 2013. “Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India.” Diabetes 62 (5): 1746-1755. doi:10.2337/db12-1077. http://dx.doi.org/10.2337/db12-1077. [Tạp chí có phản biện]

ISSN: 0012-1797 ; DOI: 10.2337/db12-1077

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Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

Walford, Geoffrey A ; Gustafsson, Stefan ; Rybin, Denis ; Stančáková, Alena ; Chen, Han ; Liu, Ching-Ti ; Hong, Jaeyoung ; Jensen, Richard A ; Rice, Ken ; Morris, Andrew P ; Mägi, Reedik ; Tönjes, Anke ; Prokopenko, Inga ; Kleber, Marcus E ; Delgado, Graciela ; Silbernagel, Günther ; Jackson, Anne U ; Appel, Emil V ; Grarup, Niels ; Lewis, Joshua P ; Montasser, May E ; Landenvall, Claes ; Staiger, Harald ; Luan, Jian’an ; Frayling, Timothy M ; Weedon, Michael N ; Xie, Weijia ; Morcillo, Sonsoles ; Martínez-Larrad, María Teresa ; Biggs, Mary L ; Chen, Yii-Der Ida ; Corbaton-Anchuelo, Arturo ; Færch, Kristine ; Gómez-Zumaquero, Juan Miguel ; Goodarzi, Mark O ; Kizer, Jorge R ; Koistinen, Heikki A ; Leong, Aaron ; Lind, Lars ; Lindgren, Cecilia ; Machicao, Fausto ; Manning, Alisa K ; Martín-Núñez, Gracia María ; Rojo-Martínez, Gemma ; Rotter, Jerome I ; Siscovick, David S ; Zmuda, Joseph M ; Zhang, Zhongyang ; Serrano-Rios, Manuel ; Smith, Ulf ; Soriguer, Federico ; Hansen, Torben ; Jørgensen, Torben J ; Linnenberg, Allan ; Pedersen, Oluf ; Walker, Mark ; Langenberg, Claudia ; Scott, Robert A ; Wareham, Nicholas J ; Fritsche, Andreas ; Häring, Hans-Ulrich ; Stefan, Norbert ; Groop, Leif ; O’connell, Jeff R ; Boehnke, Michael ; Bergman, Richard N ; Collins, Francis S ; Mohlke, Karen L ; Tuomilehto, Jaakko ; März, Winfried ; Kovacs, Peter ; Stumvoll, Michael ; Psaty, Bruce M ; Kuusisto, Johanna ; Laakso, Markku ; Meigs, James B ; Dupuis, Josée ; Ingelsson, Erik ; Florez, Jose C

Diabetes, 2016, Vol.65(10), p.3200-3211 [Tạp chí có phản biện]

ISSN: 0012-1797 ; E-ISSN: 1939-327X ; DOI: 10.2337/db16-0199 ; PMCID: 5033262 ; PMID: 27416945

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3
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Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity

Dimas, Antigone S ; Lagou, Vasiliki ; Barker, Adam ; Knowles, Joshua W ; Mägi, Reedik ; Hivert, Marie-France ; Benazzo, Andrea ; Rybin, Denis ; Jackson, Anne U ; Stringham, Heather M ; Song, Ci ; Fischer-Rosinsky, Antje ; Boesgaard, Trine Welløv ; Grarup, Niels ; Abbasi, Fahim A ; Assimes, Themistocles L ; Hao, Ke ; Yang, Xia ; Lecoeur, Cécile ; Barroso, Inês ; Bonnycastle, Lori L ; Böttcher, Yvonne ; Bumpstead, Suzannah ; Chines, Peter S ; Erdos, Michael R ; Graessler, Jurgen ; Kovacs, Peter ; Morken, Mario A ; Narisu, Narisu ; Payne, Felicity ; Stancakova, Alena ; Swift, Amy J ; Tönjes, Anke ; Bornstein, Stefan R ; Cauchi, Stéphane ; Froguel, Philippe ; Meyre, David ; Schwarz, Peter E.H ; Häring, Hans-Ulrich ; Smith, Ulf ; Boehnke, Michael ; Bergman, Richard N ; Collins, Francis S ; Mohlke, Karen L ; Tuomilehto, Jaakko ; Quertemous, Thomas ; Lind, Lars ; Hansen, Torben ; Pedersen, Oluf ; Walker, Mark ; Pfeiffer, Andreas F.H ; Spranger, Joachim ; Stumvoll, Michael ; Meigs, James B ; Wareham, Nicholas J ; Kuusisto, Johanna ; Laakso, Markku ; Langenberg, Claudia ; Dupuis, Josée ; Watanabe, Richard M ; Florez, Jose C ; Ingelsson, Erik ; Mccarthy, Mark I ; Prokopenko, Inga

Diabetes, 2014, Vol.63(6), p.2158-2171 [Tạp chí có phản biện]

ISSN: 0012-1797 ; E-ISSN: 1939-327X ; DOI: 10.2337/db13-0949 ; PMCID: 4030103 ; PMID: 24296717

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4
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No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels

Scott, Robert A ; Chu, Audrey Y ; Grarup, Niels ; Manning, Alisa K ; Hivert, Marie-France ; Shungin, Dmitry ; Tönjes, Anke ; Yesupriya, Ajay ; Barnes, Daniel ; Bouatia-Naji, Nabila ; Glazer, Nicole L ; Jackson, Anne U ; Kutalik, Zoltán ; Lagou, Vasiliki ; Marek, Diana ; Rasmussen-Torvik, Laura J ; Stringham, Heather M ; Tanaka, Toshiko ; Aadahl, Mette ; Arking, Dan E ; Bergmann, Sven ; Boerwinkle, Eric ; Bonnycastle, Lori L ; Bornstein, Stefan R ; Brunner, Eric ; Bumpstead, Suzannah J ; Brage, Soren ; Carlson, Olga D ; Chen, Han ; Chen, Yii-Der Ida ; Chines, Peter S ; Collins, Francis S ; Couper, David J ; Dennison, Elaine M ; Dowling, Nicole F ; Egan, Josephine S ; Ekelund, Ulf ; Erdos, Michael R ; Forouhi, Nita G ; Fox, Caroline S ; Goodarzi, Mark O ; Grässler, Jürgen ; Gustafsson, Stefan ; Hallmans, Göran ; Hansen, Torben ; Hingorani, Aroon ; Holloway, John W ; Hu, Frank B ; Isomaa, Bo ; Jameson, Karen A ; Johansson, Ingegerd ; Jonsson, Anna ; Jørgensen, Torben ; Kivimaki, Mika ; Kovacs, Peter ; Kumari, Meena ; Kuusisto, Johanna ; Laakso, Markku ; Lecoeur, Cécile ; Lévy-Marchal, Claire ; Li, Guo ; Loos, Ruth J.F ; Lyssenko, Valeri ; Marmot, Michael ; Marques-Vidal, Pedro ; Morken, Mario A ; Müller, Gabriele ; North, Kari E ; Pankow, James S ; Payne, Felicity ; Prokopenko, Inga ; Psaty, Bruce M ; Renström, Frida ; Rice, Ken ; Rotter, Jerome I ; Rybin, Denis ; Sandholt, Camilla H ; Sayer, Avan A ; Shrader, Peter ; Schwarz, Peter E.H ; Siscovick, David S ; Stančáková, Alena ; Stumvoll, Michael ; Teslovich, Tanya M ; Waeber, Gérard ; Williams, Gordon H ; Witte, Daniel R ; Wood, Andrew R ; Xie, Weijia ; Boehnke, Michael ; Cooper, Cyrus ; Ferrucci, Luigi ; Froguel, Philippe ; Groop, Leif ; Kao, W.H. Linda ; Vollenweider, Peter ; Walker, Mark ; Watanabe, Richard M ; Pedersen, Oluf ; Meigs, James B ; Ingelsson, Erik ; Barroso, Inês ; Florez, Jose C ; Franks, Paul W ; Dupuis, Josée ; Wareham, Nicholas J ; Langenberg, Claudia

Diabetes, 2012, Vol.61(5), p.1291-1296 [Tạp chí có phản biện]

ISSN: 0012-1797 ; E-ISSN: 1939-327X ; DOI: 10.2337/db11-0973 ; PMCID: 3331745 ; PMID: 22415877

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5
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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

Manning, Alisa ; Highland, Heather M ; Gasser, Jessica ; Sim, Xueling ; Tukiainen, Taru ; Fontanillas, Pierre ; Grarup, Niels ; Rivas, Manuel A ; Mahajan, Anubha ; Locke, Adam E ; Cingolani, Pablo ; Pers, Tune H ; Viñuela, Ana ; Brown, Andrew A ; Wu, Ying ; Flannick, Jason ; Fuchsberger, Christian ; Gamazon, Eric R ; Gaulton, Kyle J ; Im, Hae Kyung ; Teslovich, Tanya M ; Blackwell, Thomas W ; Bork-Jensen, Jette ; Burtt, Noël P ; Chen, Yuhui ; Green, Todd ; Hartl, Christopher ; Kang, Hyun Min ; Kumar, Ashish ; Ladenvall, Claes ; Ma, Clement ; Moutsianas, Loukas ; Pearson, Richard D ; Perry, John R.B ; Rayner, N. William ; Robertson, Neil R ; Scott, Laura J ; Van De Bunt, Martijn ; Eriksson, Johan G ; Jula, Antti ; Koskinen, Seppo ; Lehtimäki, Terho ; Palotie, Aarno ; Raitakari, Olli T ; Jacobs, Suzanne B.R ; Wessel, Jennifer ; Chu, Audrey Y ; Scott, Robert A ; Goodarzi, Mark O ; Blancher, Christine ; Buck, Gemma ; Buck, David ; Chines, Peter S ; Gabriel, Stacey ; Gjesing, Anette P ; Groves, Christopher J ; Hollensted, Mette ; Huyghe, Jeroen R ; Jackson, Anne U ; Jun, Goo ; Justesen, Johanne Marie ; Mangino, Massimo ; Murphy, Jacquelyn ; Neville, Matt ; Onofrio, Robert ; Small, Kerrin S ; Stringham, Heather M ; Trakalo, Joseph ; Banks, Eric ; Carey, Jason ; Carneiro, Mauricio O ; Depristo, Mark ; Farjoun, Yossi ; Fennell, Timothy ; Goldstein, Jacqueline I ; Grant, George ; Hrabé De Angelis, Martin ; Maguire, Jared ; Neale, Benjamin M ; Poplin, Ryan ; Purcell, Shaun ; Schwarzmayr, Thomas ; Shakir, Khalid ; Smith, Joshua D ; Strom, Tim M ; Wieland, Thomas ; Lindstrom, Jaana ; Brandslund, Ivan ; Christensen, Cramer ; Surdulescu, Gabriela L ; Lakka, Timo A ; Doney, Alex S.F ; Nilsson, Peter ; Wareham, Nicholas J ; Langenberg, Claudia ; Varga, Tibor V ; Franks, Paul W ; Rolandsson, Olov ; Rosengren, Anders H ; Farook, Vidya S ; Thameem, Farook ; Puppala, Sobha ; Kumar, Satish ; Lehman, Donna M ; Jenkinson, Christopher P ; Curran, Joanne E ; Hale, Daniel Esten ; Fowler, Sharon P ; Arya, Rector ; Defronzo, Ralph A ; Abboud, Hanna E ; Syvänen, Ann-Christine ; Hicks, Pamela J ; Palmer, Nicholette D ; Ng, Maggie C.Y ; Bowden, Donald W ; Freedman, Barry I ; Esko, Tõnu ; Mägi, Reedik ; Milani, Lili ; Mihailov, Evelin ; Metspalu, Andres ; Narisu, Narisu ; Kinnunen, Leena ; Bonnycastle, Lori L ; Swift, Amy ; Pasko, Dorota ; Wood, Andrew R ; Fadista, João ; Pollin, Toni I ; Barzilai, Nir ; Atzmon, Gil ; Glaser, Benjamin ; Thorand, Barbara ; Strauch, Konstantin ; Peters, Annette ; Roden, Michael ; Müller-Nurasyid, Martina ; Liang, Liming ; Kriebel, Jennifer ; Illig, Thomas ; Grallert, Harald ; Gieger, Christian ; Meisinger, Christa ; Lannfelt, Lars ; Musani, Solomon K ; Griswold, Michael ; Taylor, Herman A ; Wilson, Gregory ; Correa, Adolfo ; Oksa, Heikki ; Scott, William R ; Afzal, Uzma ; Tan, Sian-Tsung ; Loh, Marie ; Chambers, John C ; Sehmi, Jobanpreet ; Kooner, Jaspal Singh ; Lehne, Benjamin ; Cho, Yoon Shin ; Lee, Jong-Young ; Han, Bok-Ghee ; Käräjämäki, Annemari ; Qi, Qibin ; Qi, Lu ; Huang, Jinyan ; Hu, Frank B ; Melander, Olle ; Orho-Melander, Marju ; Below, Jennifer E ; Aguilar, David ; Wong, Tien Yin ; Liu, Jianjun ; Khor, Chiea-Chuen ; Chia, Kee Seng ; Lim, Wei Yen ; Cheng, Ching-Yu ; Chan, Edmund ; Tai, E Shyong ; Aung, Tin ; Linneberg, Allan ; Isomaa, Bo ; Meitinger, Thomas ; Tuomi, Tiinamaija ; Hakaste, Liisa ; Kravic, Jasmina ; Jørgensen, Marit E ; Lauritzen, Torsten ; Deloukas, Panos ; Stirrups, Kathleen E ; Owen, Katharine R ; Farmer, Andrew J ; Frayling, Timothy M ; O'Rahilly, Stephen P ; Walker, Mark ; Levy, Jonathan C ; Hodgkiss, Dylan ; Hattersley, Andrew T ; Kuulasmaa, Teemu ; Stančáková, Alena ; Barroso, Inês ; Bharadwaj, Dwaipayan ; Chan, Juliana ; Chandak, Giriraj R ; Daly, Mark J ; Donnelly, Peter J ; Ebrahim, Shah B ; Elliott, Paul ; Fingerlin, Tasha ; Froguel, Philippe ; Hu, Cheng ; Jia, Weiping ; Ma, Ronald C.W ; Mcvean, Gilean ; Park, Taesung ; Prabhakaran, Dorairaj ; Sandhu, Manjinder ; Scott, James ; Sladek, Rob ; Tandon, Nikhil ; Teo, Yik Ying ; Zeggini, Eleftheria ; Watanabe, Richard M ; Koistinen, Heikki A ; Kesaniemi, Y. Antero ; Uusitupa, Matti ; Spector, Timothy D ; Salomaa, Veikko ; Rauramaa, Rainer ; Palmer, Colin N.A ; Prokopenko, Inga ; Morris, Andrew D ; Bergman, Richard N ; Collins, Francis S ; Lind, Lars ; Ingelsson, Erik ; Tuomilehto, Jaakko ; Karpe, Fredrik ; Groop, Leif ; Jørgensen, Torben ; Hansen, Torben ; Pedersen, Oluf ; Kuusisto, Johanna ; Abecasis, Gonçalo ; Bell, Graeme I ; Blangero, John ; Cox, Nancy J ; Duggirala, Ravindranath ; Seielstad, Mark ; Wilson, James G

Diabetes, 2017, Vol.66(7), p.2019-2032 [Tạp chí có phản biện]

ISSN: 0012-1797 ; E-ISSN: 1939-327X ; DOI: 10.2337/db16-1329 ; PMCID: 5482074 ; PMID: 28341696

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A Type 2 Diabetes–Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus

Roman, Tamara S ; Cannon, Maren E ; Vadlamudi, Swarooparani ; Buchkovich, Martin L ; Wolford, Brooke N ; Welch, Ryan P ; Morken, Mario A ; Kwon, Grace J ; Varshney, Arushi ; Kursawe, Romy ; Wu, Ying ; Jackson, Anne U ; Erdos, Michael R ; Kuusisto, Johanna ; Laakso, Markku ; Scott, Laura J ; Boehnke, Michael ; Collins, Francis S ; Parker, Stephen C.J ; Stitzel, Michael L ; Mohlke, Karen L

Diabetes, 2017, Vol.66(9), p.2521-2530 [Tạp chí có phản biện]

ISSN: 0012-1797 ; E-ISSN: 1939-327X ; DOI: 10.2337/db17-0464 ; PMCID: 5860374 ; PMID: 28684635

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7
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A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study

Latva-Rasku, Aino ; Honka, Miikka-Juhani ; Stančáková, Alena ; Koistinen, Heikki A ; Kuusisto, Johanna ; Guan, Li ; Manning, Alisa K ; Stringham, Heather ; Gloyn, Anna L ; Lindgren, Cecilia M ; Collins, Francis S ; Mohlke, Karen L ; Scott, Laura J ; Karjalainen, Tomi ; Nummenmaa, Lauri ; Boehnke, Michael ; Nuutila, Pirjo ; Laakso, Markku

Diabetes, 2018, Vol.67(2), p.334-342 [Tạp chí có phản biện]

ISSN: 0012-1797 ; E-ISSN: 1939-327X ; DOI: 10.2337/db17-1142 ; PMCID: 5780065 ; PMID: 29141982

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8
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The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimers pathology

Westwood, Sarah ; Liu, Benjamine ; Baird, Alison ; Anand, Sneha ; Nevado-Holgado, Alejo ; Newby, Danielle ; Pikkarainen, Maria ; Hallikainen, Merja ; Kuusisto, Johanna ; Streffer, Johannes ; Novak, Gerald ; Blennow, Kaj ; Andreasson, Ulf ; Zetterberg, Henrik ; Smith, Ulf ; Laakso, Markku

Alzheimer's Research & Therapy, 2017 [Tạp chí có phản biện]

E-ISSN: 17589193 ; DOI: 10.1186/s13195-017-0258-6

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