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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

Manning, Alisa ; Highland, Heather M ; Gasser, Jessica ; Sim, Xueling ; Tukiainen, Taru ; Fontanillas, Pierre ; Grarup, Niels ; Rivas, Manuel A ; Mahajan, Anubha ; Locke, Adam E ; Cingolani, Pablo ; Pers, Tune H ; Viñuela, Ana ; Brown, Andrew A ; Wu, Ying ; Flannick, Jason ; Fuchsberger, Christian ; Gamazon, Eric R ; Gaulton, Kyle J ; Im, Hae Kyung ; Teslovich, Tanya M ; Blackwell, Thomas W ; Bork-Jensen, Jette ; Burtt, Noël P ; Chen, Yuhui ; Green, Todd ; Hartl, Christopher ; Kang, Hyun Min ; Kumar, Ashish ; Ladenvall, Claes ; Ma, Clement ; Moutsianas, Loukas ; Pearson, Richard D ; Perry, John R.B ; Rayner, N. William ; Robertson, Neil R ; Scott, Laura J ; Van De Bunt, Martijn ; Eriksson, Johan G ; Jula, Antti ; Koskinen, Seppo ; Lehtimäki, Terho ; Palotie, Aarno ; Raitakari, Olli T ; Jacobs, Suzanne B.R ; Wessel, Jennifer ; Chu, Audrey Y ; Scott, Robert A ; Goodarzi, Mark O ; Blancher, Christine ; Buck, Gemma ; Buck, David ; Chines, Peter S ; Gabriel, Stacey ; Gjesing, Anette P ; Groves, Christopher J ; Hollensted, Mette ; Huyghe, Jeroen R ; Jackson, Anne U ; Jun, Goo ; Justesen, Johanne Marie ; Mangino, Massimo ; Murphy, Jacquelyn ; Neville, Matt ; Onofrio, Robert ; Small, Kerrin S ; Stringham, Heather M ; Trakalo, Joseph ; Banks, Eric ; Carey, Jason ; Carneiro, Mauricio O ; Depristo, Mark ; Farjoun, Yossi ; Fennell, Timothy ; Goldstein, Jacqueline I ; Grant, George ; Hrabé De Angelis, Martin ; Maguire, Jared ; Neale, Benjamin M ; Poplin, Ryan ; Purcell, Shaun ; Schwarzmayr, Thomas ; Shakir, Khalid ; Smith, Joshua D ; Strom, Tim M ; Wieland, Thomas ; Lindstrom, Jaana ; Brandslund, Ivan ; Christensen, Cramer ; Surdulescu, Gabriela L ; Lakka, Timo A ; Doney, Alex S.F ; Nilsson, Peter ; Wareham, Nicholas J ; Langenberg, Claudia ; Varga, Tibor V ; Franks, Paul W ; Rolandsson, Olov ; Rosengren, Anders H ; Farook, Vidya S ; Thameem, Farook ; Puppala, Sobha ; Kumar, Satish ; Lehman, Donna M ; Jenkinson, Christopher P ; Curran, Joanne E ; Hale, Daniel Esten ; Fowler, Sharon P ; Arya, Rector ; Defronzo, Ralph A ; Abboud, Hanna E ; Syvänen, Ann-Christine ; Hicks, Pamela J ; Palmer, Nicholette D ; Ng, Maggie C.Y ; Bowden, Donald W ; Freedman, Barry I ; Esko, Tõnu ; Mägi, Reedik ; Milani, Lili ; Mihailov, Evelin ; Metspalu, Andres ; Narisu, Narisu ; Kinnunen, Leena ; Bonnycastle, Lori L ; Swift, Amy ; Pasko, Dorota ; Wood, Andrew R ; Fadista, João ; Pollin, Toni I ; Barzilai, Nir ; Atzmon, Gil ; Glaser, Benjamin ; Thorand, Barbara ; Strauch, Konstantin ; Peters, Annette ; Roden, Michael ; Müller-Nurasyid, Martina ; Liang, Liming ; Kriebel, Jennifer ; Illig, Thomas ; Grallert, Harald ; Gieger, Christian ; Meisinger, Christa ; Lannfelt, Lars ; Musani, Solomon K ; Griswold, Michael ; Taylor, Herman A ; Wilson, Gregory ; Correa, Adolfo ; Oksa, Heikki ; Scott, William R ; Afzal, Uzma ; Tan, Sian-Tsung ; Loh, Marie ; Chambers, John C ; Sehmi, Jobanpreet ; Kooner, Jaspal Singh ; Lehne, Benjamin ; Cho, Yoon Shin ; Lee, Jong-Young ; Han, Bok-Ghee ; Käräjämäki, Annemari ; Qi, Qibin ; Qi, Lu ; Huang, Jinyan ; Hu, Frank B ; Melander, Olle ; Orho-Melander, Marju ; Below, Jennifer E ; Aguilar, David ; Wong, Tien Yin ; Liu, Jianjun ; Khor, Chiea-Chuen ; Chia, Kee Seng ; Lim, Wei Yen ; Cheng, Ching-Yu ; Chan, Edmund ; Tai, E Shyong ; Aung, Tin ; Linneberg, Allan ; Isomaa, Bo ; Meitinger, Thomas ; Tuomi, Tiinamaija ; Hakaste, Liisa ; Kravic, Jasmina ; Jørgensen, Marit E ; Lauritzen, Torsten ; Deloukas, Panos ; Stirrups, Kathleen E ; Owen, Katharine R ; Farmer, Andrew J ; Frayling, Timothy M ; O'Rahilly, Stephen P ; Walker, Mark ; Levy, Jonathan C ; Hodgkiss, Dylan ; Hattersley, Andrew T ; Kuulasmaa, Teemu ; Stančáková, Alena ; Barroso, Inês ; Bharadwaj, Dwaipayan ; Chan, Juliana ; Chandak, Giriraj R ; Daly, Mark J ; Donnelly, Peter J ; Ebrahim, Shah B ; Elliott, Paul ; Fingerlin, Tasha ; Froguel, Philippe ; Hu, Cheng ; Jia, Weiping ; Ma, Ronald C.W ; Mcvean, Gilean ; Park, Taesung ; Prabhakaran, Dorairaj ; Sandhu, Manjinder ; Scott, James ; Sladek, Rob ; Tandon, Nikhil ; Teo, Yik Ying ; Zeggini, Eleftheria ; Watanabe, Richard M ; Koistinen, Heikki A ; Kesaniemi, Y. Antero ; Uusitupa, Matti ; Spector, Timothy D ; Salomaa, Veikko ; Rauramaa, Rainer ; Palmer, Colin N.A ; Prokopenko, Inga ; Morris, Andrew D ; Bergman, Richard N ; Collins, Francis S ; Lind, Lars ; Ingelsson, Erik ; Tuomilehto, Jaakko ; Karpe, Fredrik ; Groop, Leif ; Jørgensen, Torben ; Hansen, Torben ; Pedersen, Oluf ; Kuusisto, Johanna ; Abecasis, Gonçalo ; Bell, Graeme I ; Blangero, John ; Cox, Nancy J ; Duggirala, Ravindranath ; Seielstad, Mark ; Wilson, James G

Diabetes, 2017, Vol.66(7), p.2019-2032 [Tạp chí có phản biện]

ISSN: 0012-1797 ; E-ISSN: 1939-327X ; DOI: 10.2337/db16-1329 ; PMCID: 5482074 ; PMID: 28341696

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Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians

Hwang, Joo-Yeon ; Sim, Xueling ; Wu, Ying ; Liang, Jun ; Tabara, Yasuharu ; Hu, Cheng ; Hara, Kazuo ; Tam, Claudia H.T ; Cai, Qiuyin ; Zhao, Qi ; Jee, Sunha ; Takeuchi, Fumihiko ; Go, Min Jin ; Ong, Rick Twee Hee ; Ohkubo, Takayoshi ; Kim, Young Jin ; Zhang, Rong ; Yamauchi, Toshimasa ; So, Wing Yee ; Long, Jirong ; Gu, Dongfeng ; Lee, Nanette R ; Kim, Soriul ; Katsuya, Tomohiro ; Oh, Ji Hee ; Liu, Jianjun ; Umemura, Satoshi ; Kim, Yeon-Jung ; Jiang, Feng ; Maeda, Shiro ; Chan, Juliana C.N ; Lu, Wei ; Hixson, James E ; Adair, Linda S ; Jung, Keum Ji ; Nabika, Toru ; Bae, Jae-Bum ; Lee, Mi Hee ; Seielstad, Mark ; Young, Terri L ; Teo, Yik Ying ; Kita, Yoshikuni ; Takashima, Naoyuki ; Osawa, Haruhiko ; Lee, So-Hyun ; Shin, Min-Ho ; Shin, Dong Hoon ; Choi, Bo Youl ; Shi, Jiajun ; Gao, Yu-Tang ; Xiang, Yong-Bing ; Zheng, Wei ; Kato, Norihiro ; Yoon, Miwuk ; He, Jiang ; Shu, Xiao Ou ; Ma, Ronald C.W ; Kadowaki, Takashi ; Jia, Weiping ; Miki, Tetsuro ; Qi, Lu ; Tai, E Shyong ; Mohlke, Karen L ; Han, Bok-Ghee ; Cho, Yoon Shin ; Kim, Bong-Jo

Diabetes, 2015, Vol.64(1), p.291-298 [Tạp chí có phản biện]

ISSN: 0012-1797 ; E-ISSN: 1939-327X ; DOI: 10.2337/db14-0563 ; PMCID: 4274808 ; PMID: 25187374

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