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Late occurrence of granular dystrophy in bilateral keratoconus: penetrating keratoplasty and long-term follow-up

Rathi, Varsha M ; Vemuganti, Geeta K ; Sangwan, Virender S ; Kannabiran, Chitra

Indian journal of ophthalmology, 2011, Vol.59(5), pp.398-400 [Tạp chí có phản biện]

E-ISSN: 1998-3689 ; PMID: 21836353 Version:1 ; DOI: 10.4103/0301-4738.83624

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  • Nhan đề:
    Late occurrence of granular dystrophy in bilateral keratoconus: penetrating keratoplasty and long-term follow-up
  • Tác giả: Rathi, Varsha M ; Vemuganti, Geeta K ; Sangwan, Virender S ; Kannabiran, Chitra
  • Chủ đề: Corneal Dystrophies, Hereditary -- Etiology ; Keratoconus -- Surgery ; Keratoplasty, Penetrating -- Methods
  • Là 1 phần của: Indian journal of ophthalmology, 2011, Vol.59(5), pp.398-400
  • Mô tả: We report a rare case of keratoconus with granular dystrophy with a follow-up of two decades, documenting the sequential presentation of two diseases confirmed by histology and genetic studies. A 13-year-old boy was diagnosed in 1988 with keratoconus in both eyes (BE) based on slit-lamp biomicroscopy findings of corneal ectasia in BE accompanied by Fleischer's ring, Vogt's striae, a small, old, healed hydrops. The left eye (LE) had central corneal thinning and scar in the central area involving the mid and posterior stroma secondary to healed hydrops. Penetrating keratoplasty (PKP) was advised. The boy was lost to follow-up till 1991 and presented with white, dot-like opacities in the central cornea in the RE only, suggestive of granular corneal dystrophy. Similar findings of white, dot-like opacities were noted in the LE in 1995 and the patient subsequently underwent PKP in BE. Histopathology of corneal buttons confirmed the presence of patchy, crystal-like orange deposits, which stained...
  • Ngôn ngữ: English
  • Số nhận dạng: E-ISSN: 1998-3689 ; PMID: 21836353 Version:1 ; DOI: 10.4103/0301-4738.83624

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