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Especies de Candida y otras levaduras en la cavidad oral de pacientes diabeticos tipo 2 en Cali, Colombia.(articulo en ingles)

Suarez, Blanca Lynne ; Alvarez, Maria Ines ; de Bernal, Matilde ; Collazos, Andres

Colombia Medica, 2013, Vol.44(1), p.26(6) [Tạp chí có phản biện]

ISSN: 1657-9534

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  • Nhan đề:
    Especies de Candida y otras levaduras en la cavidad oral de pacientes diabeticos tipo 2 en Cali, Colombia.(articulo en ingles)
  • Tác giả: Suarez, Blanca Lynne ; Alvarez, Maria Ines ; de Bernal, Matilde ; Collazos, Andres
  • Là 1 phần của: Colombia Medica, 2013, Vol.44(1), p.26(6)
  • Mô tả: Objetivos: Determinar la prevalencia de las especies de Candida y estudiar factores asociados a la colonizacion de la cavidad oral en pacientes con diabetes mellitus tipo 2. Metodos: 107 diabeticos se clasificaron en controlados y no controlados, de acuerdo con los valores de hemoglobina glucosilada. A cada paciente se le tomo una muestra de saliva estimulada y un enjuague oral, la primera se utilizo para determinar el pH y la tasa de flujo salival, la segunda para buscar levaduras. Ademas, se determino el estado de salud oral mediante los indices CPO-D de Klein y Palmer para denticion permanente, el de placa bacteriana de O'Leary y un periodontograma. Resultados: Se hallaron levaduras en el 74,8% de los pacientes. Un total de 36 de 52 sujetos con diabetes controlada presentaron levaduras y 44 en los no controlados; sin diferencias significativas (p = 0,2) entre la presencia de levaduras y el control de la glucemia. El mayor numero de aislamientos correspondio a C. albicans, seguido de C. parapsilosis. Los individuos no controlados presentaron de manera significante un porcentaje mas alto de levaduras diferentes a C. albicans (p = 0,049). Solo se encontro asociacion entre el aislamiento de levaduras y la baja tasa de flujo salival Conclusion: Se encontro un alto porcentaje de colonizacion por Candida, y en los individuos no controlados hubo mayor diversidad de especies. El amplio rango de UFC/ml hallada tanto en pacientes con candidiasis oral como sin ella no permitio establecer colonizacion y enfermedad. Palabras claves: Diabetes mellitus tipo 2, Candida sp, candidiasis, Prothotheca, Colombia. Objective: To determine the prevalence of Candida species and to study factors associated to oral cavity colonization in patients with type 2 diabetes mellitus. Methods: A total of 107 diabetics were classified into controlled and uncontrolled according to glycosylated hemoglobin values. Each patient was assessed for stimulated salivary flow rates, pH, and an oral rinse to search for yeast. The study also determined the state of oral health via Klein and Palmer CPO indexes for permanent dentition, dental plaque by O'Leary, and a periodontal chart. Results: We found yeasts in 74.8% of the patients. A total of 36 of the 52 subjects with controlled diabetes presented yeasts and 44 in the uncontrolled; no significant differences (p = 0.2) were noted among the presence of yeasts and the control of blood glucose. The largest number of isolates corresponded to C. albicans, followed by C. parapsilosis. Uncontrolled individuals presented a significantly higher percentage of yeast different from C. albicans (p = 0.049). Conclusions: We found a high percentage of Candida colonization and uncontrolled individuals had greater diversity of species. The wide range of CFU/ml found both in patients with oral candidiasis, as well as in those without it did not permit distinguishing between colonization and disease. We only found association between isolation of yeasts and the low rate of salivary flow. Keywords: Type 2 diabetes mellitus, Candida sp, candidiasis, Prototheca, Colombia
  • Ngôn ngữ: English
  • Số nhận dạng: ISSN: 1657-9534

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