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Long-Term Follow-Up of Elective Chronic Total Coronary Occlusion Angioplasty: Analysis From the U.K. Central Cardiac Audit Database: Analysis From the U.K. Central Cardiac Audit Database

George, Sudhakar ; Cockburn, James ; Clayton, Tim C. ; Ludman, Peter ; Cotton, James ; Spratt, James ; Redwood, Simon ; de Belder, Mark ; de Belder, Adam ; Hill, Jonathan ; Hoye, Angela ; Palmer, Nick ; Rathore, Sudhir ; Gershlick, Anthony ; Di Mario, Carlo ; Hildick-Smith, David

Journal of the American College of Cardiology, 22 July 2014, Vol.64(3), pp.235-243 [Tạp chí có phản biện]

ISSN: 0735-1097 ; DOI: 10.1016/j.jacc.2014.04.040

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  • Nhan đề:
    Long-Term Follow-Up of Elective Chronic Total Coronary Occlusion Angioplasty: Analysis From the U.K. Central Cardiac Audit Database: Analysis From the U.K. Central Cardiac Audit Database
  • Tác giả: George, Sudhakar ; Cockburn, James ; Clayton, Tim C. ; Ludman, Peter ; Cotton, James ; Spratt, James ; Redwood, Simon ; de Belder, Mark ; de Belder, Adam ; Hill, Jonathan ; Hoye, Angela ; Palmer, Nick ; Rathore, Sudhir ; Gershlick, Anthony ; Di Mario, Carlo ; Hildick-Smith, David
  • Chủ đề: Chronic Total Occlusions ; Percutaneous Coronary Intervention ; Registry ; Bcis ; Cabg ; Cto ; Lad ; Lcx ; Mi ; PCI ; RCA ; Timi
  • Là 1 phần của: Journal of the American College of Cardiology, 22 July 2014, Vol.64(3), pp.235-243
  • Mô tả: BackgroundChronic total occlusion (CTO) is common, being reported in 18% to 30% of patients undergoing coronary angiography. Percutaneous coronary intervention (PCI) is usually performed to relieve anginal symptoms, but data are emerging to suggest that there may also be a mortality benefit. ObjectivesThis study aimed to compare outcomes of patients with successful versus unsuccessful PCI to a CTO. MethodsWe analyzed the U.K. Central Cardiac Audit Database for all CTO PCI cases carried out in England and Wales between January 1, 2005, and December 31, 2009. Vital status in September 2010 was obtained from the Medical Research Information Service. ResultsA total of 13,443 patients (78.8% male) had a mean age of 63.5 years and underwent 14,439 CTO procedures. CTO PCI was successful in 10,199 cases (70.6%). During follow-up of 2.65 years (interquartile range: 1.59 to 3.83 years), successful PCI of at least 1 CTO was associated with improved survival (hazard ratio [HR]: 0.72; 95% CI: 0.62 to 0.83; p < 0.001). Complete revascularization was associated with improved survival compared with partial revascularization (HR: 0.70; 95% CI: 0.56 to 0.87; p = 0.002) or failed revascularization (HR: 0.61; 95% CI: 0.50 to 0.74; p < 0.001). ConclusionsSuccessful CTO PCI was associated with improved long-term survival. The improvement was greatest in patients when complete revascularization was achieved. The identity of the successfully treated occluded vessel was not associated with differences in outcome.
  • Ngôn ngữ: English
  • Số nhận dạng: ISSN: 0735-1097 ; DOI: 10.1016/j.jacc.2014.04.040

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