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High concordance between mental stress-induced and adenosine-induced myocardial ischemia assessed using SPECT in heart failure patients: Hemodynamic and biomarker correlates

Wawrzyniak, A.J. ; Dilsizian, V. ; Krantz, D.S. ; Harris, K.M. ; Smith, M.F. ; Shankovich, A. ; Whittaker, K.S. ; Rodriguez, G.A. ; Gottdiener, J.S. ; Li, J. ; Kop, W.J. ; Gottlieb, S.S.; Medical and Clinical Psychology

Journal of Nuclear Medicine, 2015, Vol.56(10), pp.1527-1533 [Tạp chí có phản biện]

ISSN: ; ISSN: 0161-5505

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  • Nhan đề:
    High concordance between mental stress-induced and adenosine-induced myocardial ischemia assessed using SPECT in heart failure patients: Hemodynamic and biomarker correlates
  • Tác giả: Wawrzyniak, A.J. ; Dilsizian, V. ; Krantz, D.S. ; Harris, K.M. ; Smith, M.F. ; Shankovich, A. ; Whittaker, K.S. ; Rodriguez, G.A. ; Gottdiener, J.S. ; Li, J. ; Kop, W.J. ; Gottlieb, S.S.
  • Medical and Clinical Psychology
  • Chủ đề: Medicine
  • Là 1 phần của: Journal of Nuclear Medicine, 2015, Vol.56(10), pp.1527-1533
  • Mô tả: Mental stress can trigger myocardial ischemia, but the prevalence of mental stress–induced ischemia in congestive heart failure (CHF) patients is unknown. We characterized mental stress–induced and adenosine-induced changes in myocardial perfusion and neurohormonal activation in CHF patients with reduced left-ventricular function using SPECT to precisely quantify segment-level myocardial perfusion. Methods: Thirty-four coronary artery disease patients (mean age ± SD, 62 ± 10 y) with CHF longer than 3 mo and ejection fraction less than 40% underwent both adenosine and mental stress myocardial perfusion SPECT on consecutive days. Mental stress consisted of anger recall (anger-provoking speech) followed by subtraction of serial sevens. The presence and extent of myocardial ischemia was quantified using the conventional 17-segment model. Results: Sixty-eight percent of patients had 1 ischemic segment or more during mental stress and 81% during adenosine. On segment-by-segment analysis, perfusion...
  • Ngôn ngữ: English
  • Số nhận dạng: ISSN: ; ISSN: 0161-5505

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