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Anaemia is of prognostic significance in patients with oesophageal adenocarcinoma

Tanswell, I ; Steed, H ; Butterworth, J ; Townson, G

The journal of the Royal College of Physicians of Edinburgh, September 2011, Vol.41(3), pp.206-10 [Tạp chí có phản biện]

E-ISSN: 2042-8189 ; PMID: 21949914 Version:1 ; DOI: 10.4997/JRCPE.2011.304

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  • Nhan đề:
    Anaemia is of prognostic significance in patients with oesophageal adenocarcinoma
  • Tác giả: Tanswell, I ; Steed, H ; Butterworth, J ; Townson, G
  • Chủ đề: Anemia ; Adenocarcinoma -- Mortality ; Carcinoma, Squamous Cell -- Mortality ; Esophageal Neoplasms -- Mortality ; Hemoglobins -- Metabolism
  • Là 1 phần của: The journal of the Royal College of Physicians of Edinburgh, September 2011, Vol.41(3), pp.206-10
  • Mô tả: Anaemia is common in a wide range of malignancies and individual studies have demonstrated it to be an independent prognostic marker for survival in certain cancer types. The study population consisted of 171 patients: 77 anaemic and 94 non-anaemic. Sixty per cent of the study population had adenocarcinoma with 37% having squamous cell carcinoma. Late-stage disease occurred in 80% of individuals. There was no significant difference in survival times between the two groups (p=0.1), and after adjusting for confounding factors including age, sex, stage and physical status (p=0.8). Anaemic individuals with adenocarcinoma suffered a poorer survival probability compared to those with normal haemoglobon level (p=0.02). Anaemia is common at diagnosis in oesophageal cancer and was found to be a significant prognostic indicator of survival in adenocarcinoma, but not squamous cell carcinoma.
  • Ngôn ngữ: English
  • Số nhận dạng: E-ISSN: 2042-8189 ; PMID: 21949914 Version:1 ; DOI: 10.4997/JRCPE.2011.304

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