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Patterning droplets with durotaxis.(APPLIED PHYSICAL SCIENCES: BIOPHYSICS AND COMPUTATIONAL BIOLOGY)(Report)(Author abstract)

Style, Robert W. ; Che, Yonglu ; Park, Su Ji ; Weon, Byung Mook ; Je, Jung Ho ; Hyland, Callen ; German, Guy K. ; Power, Michael P. ; Wilen, Larry A. ; Wettlaufer, John S. ; Dufresne, Eric R.

Proceedings of the National Academy of Sciences of the United States, July 30, 2013, Vol.110(31), p.12541(4) [Tạp chí có phản biện]

ISSN: 0027-8424

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  • Nhan đề:
    Patterning droplets with durotaxis.(APPLIED PHYSICAL SCIENCES: BIOPHYSICS AND COMPUTATIONAL BIOLOGY)(Report)(Author abstract)
  • Tác giả: Style, Robert W. ; Che, Yonglu ; Park, Su Ji ; Weon, Byung Mook ; Je, Jung Ho ; Hyland, Callen ; German, Guy K. ; Power, Michael P. ; Wilen, Larry A. ; Wettlaufer, John S. ; Dufresne, Eric R.
  • Chủ đề: Microfluidics -- Research ; Computational Biology -- Research ; Biophysics -- Research
  • Là 1 phần của: Proceedings of the National Academy of Sciences of the United States, July 30, 2013, Vol.110(31), p.12541(4)
  • Mô tả: Numerous cell types have shown a remarkable ability to detect and move along gradients in stiffness of an underlying substrate--a process known as durotaxis. The mechanisms underlying durotaxis are still unresolved, but generally believed to involve active sensing and locomotion. Here, we show that simple liquid droplets also undergo durotaxis. By modulating substrate stiffness, we obtain fine control of droplet position on soft, flat substrates. Unlike other control mechanisms, droplet durotaxis works without imposing chemical, thermal, electrical, or topographical gradients. We show that droplet durotaxis can be used to create large-scale droplet patterns and is potentially useful for many applications, such as microfluidics, thermal control, and microfabrication. droplet control | elasticity | soft matter | wetting | mechanosensing www.pnas.org/cgi/doi/10.1073/pnas.1307122110
  • Ngôn ngữ: English
  • Số nhận dạng: ISSN: 0027-8424

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