skip to main content
Ngôn ngữ:
Giới hạn tìm kiếm: Giới hạn tìm kiếm: Dạng tài nguyên Hiển thị kết quả với: Hiển thị kết quả với: Chỉ mục

The molecular basis for attractive salt-taste coding in Drosophila.(REPORTS)(Author abstract)

Zhang, Yali V. ; Ni, Jinfei ; Montell, Craig

Science, June 14, 2013, Vol.340(6138), p.1334(5) [Tạp chí có phản biện]

ISSN: 0036-8075

Toàn văn sẵn có

Trích dẫn Trích dẫn bởi
  • Nhan đề:
    The molecular basis for attractive salt-taste coding in Drosophila.(REPORTS)(Author abstract)
  • Tác giả: Zhang, Yali V. ; Ni, Jinfei ; Montell, Craig
  • Là 1 phần của: Science, June 14, 2013, Vol.340(6138), p.1334(5)
  • Mô tả: Below a certain level, table salt (NAG) is beneficial for animals, whereas excessive salt is harmful However, it remains unclear how low- and high-salt taste perceptions are differentially encoded. We identified a salt-taste coding mechanism in Drosophila melanogaster. Flies use distinct types of gustatory receptor neurons (GRNs) to respond to different concentrations of salt. We demonstrated that a member of the newly discovered ionotropic glutamate receptor (IR) family, IR76b, functioned in the detection of low salt and was a [Na.sup.+] channel. The loss of IR76b selectively impaired the attractive pathway, leaving salt-aversive GRNs unaffected. Consequently, tow salt became aversive. Our work demonstrated that the opposing behavioral responses to low and high salt were determined largely by an elegant bimodal, switch system operating in GRNs. 10.1126/science.1234133
  • Ngôn ngữ: English
  • Số nhận dạng: ISSN: 0036-8075

Đang tìm Cơ sở dữ liệu bên ngoài...