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THE CONCEPT OF DEADSPACE WITH SPECIAL REFERENCE TO THE SINGLE BREATH TEST FOR CARBON DIOXIDE

Fletcher, R ; Jonson, B ; Cumming, G ; Brew, J

British Journal of Anaesthesia, January 1981, Vol.53(1), pp.77-88 [Tạp chí có phản biện]

ISSN: 0007-0912 ; E-ISSN: 1471-6771 ; DOI: 10.1093/bja/53.1.77

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  • Nhan đề:
    THE CONCEPT OF DEADSPACE WITH SPECIAL REFERENCE TO THE SINGLE BREATH TEST FOR CARBON DIOXIDE
  • Tác giả: Fletcher, R ; Jonson, B ; Cumming, G ; Brew, J
  • Chủ đề: Carbon Dioxide ; Respiratory Dead Space ; Breath Tests -- Methods
  • Là 1 phần của: British Journal of Anaesthesia, January 1981, Vol.53(1), pp.77-88
  • Mô tả: We present a review and a theoretical analysis of factors determining airway deadspace ( D ) and alveolar deadspace ( D ), the two constituents of physiological deadspace ( D ). D is the volume of gas between the lips and the alveolar/fresh gas interface, the location of which is determined by inspiratory flow pattern and airway geometry. D can be caused by incomplete alveolar gas mixing and associated / mismatching within the terminal respiratory units, temporal / mismatching within units, spatial / mismatching between units, and venous admixture. Most causes of D are influenced by inspiratory flow pattern and the time available for gas diffusion and distribution. Analysis can be made from the single breath test for carbon dioxide (SBT–CO ) which is the plot of fraction of carbon dioxide in expired gas against expired volume. The common causes of D are associated with a sloping SBT-CO phase III. Combination of SBT-CO with PaCO yields D and D . A sloping phase III with a negative arterial-end-tidal co gradient implies compensation by perfusion for early emptying, overventilated alveoli.
  • Ngôn ngữ: English
  • Số nhận dạng: ISSN: 0007-0912 ; E-ISSN: 1471-6771 ; DOI: 10.1093/bja/53.1.77

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