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Recurrence in patients with clinically early-stage papillary thyroid carcinoma according to tumor size and surgical extent

Kim, Ji Won ; Roh, Jong-Lyel ; Gong, Gyungyup ; Cho, Kyung-Ja ; Choi, Seung-Ho ; Nam, Soon Yuhl ; Kim, Sang Yoon

The American Journal of Surgery, September 2016, Vol.212(3), pp.419-425.e1 [Tạp chí có phản biện]

ISSN: 0002-9610 ; E-ISSN: 1879-1883 ; DOI: 10.1016/j.amjsurg.2015.12.015

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  • Nhan đề:
    Recurrence in patients with clinically early-stage papillary thyroid carcinoma according to tumor size and surgical extent
  • Tác giả: Kim, Ji Won ; Roh, Jong-Lyel ; Gong, Gyungyup ; Cho, Kyung-Ja ; Choi, Seung-Ho ; Nam, Soon Yuhl ; Kim, Sang Yoon
  • Chủ đề: Papillary Thyroid Carcinoma ; Surgery ; Recurrence ; Tumor Size ; Risk Factor
  • Là 1 phần của: The American Journal of Surgery, September 2016, Vol.212(3), pp.419-425.e1
  • Mô tả: To investigate whether post-treatment recurrence differs by tumor size or surgical extent in clinically early-stage papillary thyroid carcinoma (PTC) patients. A total of 1,041 surgical patients with PTC 4 cm or less and no clinical evidence of metastases to regional or distant sites were included. Cox proportional hazard models were used to identify the clinicopathological variables predictive of post-treatment recurrence. Central nodal involvement was found in 313 (34.1%) of 918 patients who underwent prophylactic central lymph node dissection. For the median follow-up of 83 months, 25 (2.4%) of 1,041 patients had a regional recurrence and 12 (1.2%) patients died of other causes. Male gender, tumor size, extranodal extension, and positive resection margin remained independent variables predictive of recurrence by multivariate analysis ( < .05 each). There was no significant impact of age (<45 vs ≥45 years, = .944) or surgical extent (unilateral vs bilateral thyroidectomy, = .776) on recurrence. Tumor size in patients with PTC of 4 cm or less is an important predictive factor for post-treatment recurrence.
  • Ngôn ngữ: English
  • Số nhận dạng: ISSN: 0002-9610 ; E-ISSN: 1879-1883 ; DOI: 10.1016/j.amjsurg.2015.12.015

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