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Cerebellum and Brainstem-8

Schmahmann, Jeremy D.

Brain Mapping: The Systems, Chapter 8, pp.207-259

ISBN: 978-0-12-692545-6 ; DOI: 10.1016/B978-012692545-6/50010-6

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  • Nhan đề:
    Cerebellum and Brainstem-8
  • Tác giả: Schmahmann, Jeremy D.
  • Là 1 phần của: Brain Mapping: The Systems, Chapter 8, pp.207-259
  • Mô tả: This chapter presents the relationship between structure and function in the cerebellum and brainstem. Ablation experiments continue to be a valuable tool in contemporary studies of cerebellar function in animal models. This approach has been used to demonstrate that acquisition, retention, and performance of the conditioned learning response is critically dependent upon the cerebellum. Motor learning deficits have been produced in the rat model using the cerebellar ablation paradigm. Reversible ablation paradigms are now possible using functional inactivation techniques. Physiological studies of the deep cerebellar nuclei show that each contains at least one more or less complete body map and controls different aspects of motor movement. The dentate controls synergist muscles in visually guided movements such as pinching and reaching; the interpositus controls agonist antagonist synergy and stretch reflexes at a single joint; and the fastigial nucleus controls synergists in upright stance and locomotion. These findings are consistent with the clinical observation that cerebellar lesions impair compound movements more than simple movements.
  • Năm xuất bản: 2000
  • Ngôn ngữ: English;French;German;Italian;Polish
  • Số nhận dạng: ISBN: 978-0-12-692545-6 ; DOI: 10.1016/B978-012692545-6/50010-6

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