skip to main content
Ngôn ngữ:
Giới hạn tìm kiếm: Giới hạn tìm kiếm: Dạng tài nguyên Hiển thị kết quả với: Hiển thị kết quả với: Chỉ mục

Empowering the detection of ChIP-seq “basic peaks” (bPeaks) in small eukaryotic genomes with a web user-interactive interface

Thomas Denecker ; Gaëlle Lelandais

BMC Research Notes, 01 October 2018, Vol.11(1), pp.1-7 [Tạp chí có phản biện]

E-ISSN: 1756-0500 ; DOI: 10.1186/s13104-018-3802-y

Toàn văn sẵn có

Trích dẫn Trích dẫn bởi
  • Nhan đề:
    Empowering the detection of ChIP-seq “basic peaks” (bPeaks) in small eukaryotic genomes with a web user-interactive interface
  • Tác giả: Thomas Denecker ; Gaëlle Lelandais
  • Chủ đề: Chip-Seq ; Peak Calling ; Protein DNA-Binding Sites ; Small Eukaryotic Genomes ; Bpeaks ; Biology
  • Là 1 phần của: BMC Research Notes, 01 October 2018, Vol.11(1), pp.1-7
  • Mô tả: Abstract Objective bPeaks is a peak calling program to detect protein DNA-binding sites from ChIPseq data in small eukaryotic genomes. The simplicity of the bPeaks method is well appreciated by users, but its use via an R package is challenging and time-consuming for people without programming skills. In addition, user feedback has highlighted the lack of a convenient way to carefully explore bPeaks result files. In this context, the development of a web user interface represents an important added value for expanding the bPeaks user community. Results We developed a new bPeaks application (bPeaks App). The application allows the user to perform all the peak-calling analysis steps with bPeaks in a few mouse clicks via a web browser. We added new features relative to the original R package, particularly the possibility to import personal annotation files to compare the location of the detected peaks with specific genomic elements of interest of the user, in any organism, and a new organization of the result files which are directly manageable via a user-interactive genome browser. This significantly improves the ability of the user to explore all detected basic peaks in detail.
  • Ngôn ngữ: English
  • Số nhận dạng: E-ISSN: 1756-0500 ; DOI: 10.1186/s13104-018-3802-y

Đang tìm Cơ sở dữ liệu bên ngoài...