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Occurrence of antibiotic resistance genes and mobile genetic elements in enterococci and genomic DNA during anaerobic digestion of pharmaceutical waste sludge with different pretreatments

Tong, Juan ; Lu, Xueting ; Zhang, Junya ; Sui, Qianwen ; Wang, Rui ; Chen, Meixue ; Wei, Yuansong

Bioresource Technology, July 2017, Vol.235, pp.316-324 [Tạp chí có phản biện]

ISSN: 0960-8524 ; E-ISSN: 1873-2976 ; DOI: 10.1016/j.biortech.2017.03.104

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  • Nhan đề:
    Occurrence of antibiotic resistance genes and mobile genetic elements in enterococci and genomic DNA during anaerobic digestion of pharmaceutical waste sludge with different pretreatments
  • Tác giả: Tong, Juan ; Lu, Xueting ; Zhang, Junya ; Sui, Qianwen ; Wang, Rui ; Chen, Meixue ; Wei, Yuansong
  • Chủ đề: Antibiotic Resistance ; Enterococci ; Pharmaceutical Waste Sludge ; Anaerobic Digestion ; Pretreatment ; Agriculture ; Engineering ; Chemistry
  • Là 1 phần của: Bioresource Technology, July 2017, Vol.235, pp.316-324
  • Mô tả: Pharmaceutical waste sludge harbors large amounts of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs), and it is necessary to study the reduction of ARGs and MGEs during sludge treatment. Therefore, the antibiotic resistance phenotypes and genotypes of enterococci, and the ARGs and MGEs in genomic DNA were investigated during anaerobic digestion (AD) with microwave (MW), thermal hydrolysis (TH) and ozone pretreatment. Results showed that sludge pretreatment increased the occurrence of the resistance phenotypes and genotypes of enterococci. During AD, the resistance of enterococci to macrolides decreased, except for in the MW-pretreated sludge. Horizontal gene transfer and co-occurrence of B and M in enterococci resulted in increased tetracycline resistance of enterococci throughout the sludge treatment. MGEs such as 1, IS and Tn had a significant effect on the...
  • Ngôn ngữ: English
  • Số nhận dạng: ISSN: 0960-8524 ; E-ISSN: 1873-2976 ; DOI: 10.1016/j.biortech.2017.03.104

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